The Rhino Orphanage in Limpopo Province said Jazz the giraffe was only 2 days old when he was found alone and in a coma.
The giraffe was brought to the facility, where anti-poaching dog Hunter quickly took a shine to the young animal.
Carers said Hunter refused to eat until Jazz emerged from the coma and his health started to improve.
The sanctuary said Hunter is a “special animal” and spends all day watching over Jazz, whose health is rapidly improving.
Jazz is expected to eventually be returned to the wild.